Motif ID: HOX{A5,B5}.p2

Z-value: 1.276


Transcription factors associated with HOX{A5,B5}.p2:

Gene SymbolEntrez IDGene Name
HOXA5 3202 homeobox A5
HOXB5 3215 homeobox B5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
HOXA5chr7_-_27183225-0.481.4e-02Click!
HOXB5chr17_-_46671043-0.481.6e-02Click!


Activity profile for motif HOX{A5,B5}.p2.

activity profile for motif HOX{A5,B5}.p2


Sorted Z-values histogram for motif HOX{A5,B5}.p2

Sorted Z-values for motif HOX{A5,B5}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A5,B5}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_17958773 4.091 JAK3
Janus kinase 3
chr4_-_76944585 4.062 NM_001565
 CXCL10
chemokine (C-X-C motif) ligand 10
chr22_-_36556781 3.517 NM_145640
 APOL3
apolipoprotein L, 3
chr19_+_8117645 3.143 NM_001201359
NM_005624
 CCL25

chemokine (C-C motif) ligand 25

chr3_-_127541160 2.920 NM_007283
 MGLL
monoglyceride lipase
chr12_+_56075329 2.410 NM_152637
 METTL7B
methyltransferase like 7B
chr6_-_29527477 2.168 UBD
ubiquitin D
chr16_-_84651639 2.154 NM_021149
 COTL1
coactosin-like 1 (Dictyostelium)
chr16_+_86544104 2.077 NM_001451
 FOXF1
forkhead box F1
chr7_-_47622127 1.970 TNS3
tensin 3
chr6_+_31543340 1.846 NM_000594
 TNF
tumor necrosis factor
chr1_+_205236591 1.845 TMCC2
transmembrane and coiled-coil domain family 2
chr1_-_12677347 1.794 NM_004753
 DHRS3
dehydrogenase/reductase (SDR family) member 3
chr6_+_31554975 1.722 NM_001166538
NM_007161
NM_205840
 LST1


leukocyte specific transcript 1


chr11_+_20070609 1.698 NAV2
neuron navigator 2
chr12_+_56075418 1.667 METTL7B
methyltransferase like 7B
chr12_+_54955226 1.631 NM_001165975
 PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr2_+_152214105 1.613 NM_007115
 TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr6_+_36644236 1.605 NM_001220777
NM_078467
 CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

chr19_+_57106622 1.574 NM_021216
 ZNF71
zinc finger protein 71

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
14.99 4.11e-05 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
13.32 1.76e-04 GO:0048880 sensory system development
13.32 1.76e-04 GO:0048892 lateral line nerve development
13.32 1.76e-04 GO:0048895 lateral line nerve glial cell differentiation
13.32 1.76e-04 GO:0048925 lateral line system development
13.32 1.76e-04 GO:0048937 lateral line nerve glial cell development
13.32 1.76e-04 GO:0050935 iridophore differentiation
10.90 1.45e-03 GO:0060600 dichotomous subdivision of an epithelial terminal unit
9.99 3.30e-03 GO:0048846 axon extension involved in axon guidance
9.99 3.30e-03 GO:0090184 positive regulation of kidney development
9.14 1.40e-03 GO:0048485 sympathetic nervous system development
7.99 2.30e-02 GO:0030513 positive regulation of BMP signaling pathway
7.99 2.30e-02 GO:0048484 enteric nervous system development
6.53 3.23e-02 GO:0030318 melanocyte differentiation
6.53 3.23e-02 GO:0050931 pigment cell differentiation
1.18 2.55e-03 GO:0065007 biological regulation
1.18 6.77e-03 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.22 3.25e-02 GO:0034702 ion channel complex
1.35 1.36e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
4.05 7.52e-03 GO:0008301 DNA bending activity
3.00 2.56e-02 GO:0016566 specific transcriptional repressor activity